Physicochemical properties in relation to biological action, Unit-I B.Pharm 4th Semester Notes PDF

 

• Introduction to Medicinal Chemistry
• History and development of medicinal chemistry
• Physicochemical properties in relation to biological action
• Ionization, Solubility, Partition Coefficient, Hydrogen bonding, Protein binding, Chelation, Bioisosterism, Optical and Geometrical isomerism.
• Drug metabolisam
• Drug metabolism principles- Phase I and Phase II. 
• Factors affecting drug metabolism including stereo chemical aspects








Introduction to Medicinal Chemistry

History and Development of Medicinal Chemistry

Physicochemical properties in relation to biological action

• Ionization
• Solubility
• Partition Coefficient
• Hydrogen bonding
• Protein binding
• Chelation
• Bioisosterism
• Optical and Geometrical isomerism