MCQs on Pharmaceutical Incompatibility Pharmaceutics Question Answers

1.    Which is the type of Pharmaceutical Incompatibilities are:
a)    Physical & Chemical Incompatibilities
b)    Therapeutic Incompatible 
c)    Both a and b
d)    None of these

 

2.    Incompatibilities may occur during:
a)    Compounding and Formulation
b)    Manufacturing and Packaging
c)    Dispensing, Storage or Administration of Drug
d)    All of the above

 

3.    Incompatibility may be detected by:
a)    Changes in the physical and chemical state
b)    Changes in storage conditions
c)    Changes in packing material
d)    All of the above

 

4.    Interaction between two or more substances which may lead to change in color, odor, taste,  viscosity and morphology is termed as
a)    Physical Incompatibility
b)    Chemical Incompatibility
c)    Organoleptic Incompatibility
d)    None of the above

 

5.    Which type of incompatibility may occur in following preparation:
Mixture of chalk:
      Rx
        Chalk powder – 2g
        Tincture catechu – 2ml
        Cinnamon water – 2ml
a)    Physical incompatibility
b)    Chemical Incompatibility
c)    Therapeutic 
d)    Organoleptic

 

6.    There are ___ types of Pharmaceutical incompatibility
a)    One
b)    Two
c)    Three
d)    Four

7.    The incompatibility arising out of prescribing together of Diazepam and Caffeine is:
a)    Physical 
b)    Chemical 
c)    Therapeutic 
d)    Both a and b

8.    Alkaloid incompatibility can be corrected by use of
a)    Alkaloidal salts with alkaloid substances 
b)    Alkaloidal salts with soluble iodides 
c)    Alkaloidal salts with tannins  
d)    All of the above

9.    Therapeutic Incompatibility may occur due to:
a)    Error in dosage or Wrong dose/dosage form 
b)    Contra-indicated drugs 
c)    Synergistic and antagonistic drugs 
d)    All of the above

10.    When aspirin is prescribed with paracetamol, which incompatibility may occur:

a)    Physical
b)    Chemical
c)    Therapeutic
d)    All of these

11.    Therapeutic Incompatibility may include following manifestations:
a)    Drug interaction
b)    Synergistic effect
c)    Change in viscosity
d)    Both a and b

12.    “Tetracycline is inactivated by calcium present in milk. So, it should not be taken with milk.” Name the type of incompatible discussed in the above example.
a)    Therapeutic
b)    Physical
c)    Chemical
d)    None of these

13.    “Amphetamines show its antagonists effect with the barbiturates" Which type of incompatibility discussed in the above example.
a)    Physical
b)    Chemical
c)    Precipitation
d)    Therapeutic

14.    Chemical Incompatibility may occur due to:
a)    pH change or Oxidation-reduction reactions 
b)    Acid-base hydrolysis or Double decomposition 
c)    Complex formation     
d)    All of the above

15.    Chemical Incompatibility may include following manifestations:
a)    Color change
b)    pH change or effervescence 
c)    Explosion or decomposition
d)    All of the above

16.    Chemical Incompatibility may occur due to:
a)    Chemical Interaction, Prescriber’s Fault, Damaged Labelling 
b)    Irregular administration
c)    Increased Dose
d)    None of these

17.    Immiscibility may cause which type of incompatibility:
a)    Physical
b)    Chemical
c)    Therapeutical
d)    None of these

18.    Presence of micro – organism may cause
a)    Therapeutic incompatibility
b)    Physical Incompatibility
c)    Both a and b
d)    None of these

19.    While preparing a preparation, Resins are insoluble in water. Which type of incompatibility may occurs:
a)    Physical due to precipitation
b)    Physical due to liquefaction
c)    Chemical due to resin water reaction
d)    No incompatibility occurs

20.    The change in the formulation is needed with a compound having equal therapeutic value to overcome incompatibility is:
a)    Adjusted incompatibility
b)    Tolerated incompatibility
c)    Therapeutic Incompatibility
d)    None of these